Buffalo Bills
AFC East
4-1
PCT .800
Week 1vs
Carolina PanthersW29-14Week 2@
Cleveland BrownsW31-7Week 3vs
Pittsburgh SteelersW28-27Week 1@
Houston TexansW36-31Week 2vs
Detroit LionsW41-31Week 3vs
Los Angeles ChargersW24-16Week 4vs
New England PatriotsL26-29Week 5@
Los Angeles RamsW37-34Week 6@
Las Vegas RaidersW33-30Week 8vs
Baltimore Ravens01 NovWeek 9@
Minnesota Vikings10 NovWeek 10@
New York Jets15 NovWeek 11vs
Miami Dolphins22 NovWeek 12vs
Kansas City Chiefs27 NovWeek 13@New England Patriots06 DecWeek 14@
Green Bay Packers14 DecWeek 15vs
Chicago Bears20 DecWeek 16@
Denver Broncos25 DecWeek 17@Miami Dolphins03 JanWeek 18vsNew York Jets10 Jan
| # | Player | Position | Age | College |
|---|---|---|---|---|
| 47 | Christian Benford | CB | 26 | Villanova |
| 21 | Davison Igbinosun | CB | 22 | Ohio State |
| 23 | Dee Alford | CB | 28 | Tusculum |
| 41 | Kani Walker | CB | 23 | Arkansas |
| 1 | Maxwell Hairston | CB | 23 | Kentucky |
| 33 | Te'Cory Couch | CB | 27 | Miami |
| 94 | Landon Jackson | DE | 23 | Arkansas |
| 55 | Michael Hoecht | DE | 29 | Brown |
| 51 | Mike Danna | DE | 28 | Michigan |
| 96 | Deone Walker | DT | 22 | Kentucky |
| 90 | DeWayne Carter | DT | 25 | Duke |
| 91 | Ed Oliver | DT | 28 | Houston |
| 97 | Greg Gaines | DT | 30 | Washington |
| 98 | T.J. Sanders | DT | 23 | South Carolina |
| 9 | Bradley Chubb | LB | 30 | NC State |
| 42 | Dorian Williams | LB | 25 | Tulane |
| 15 | Greg Rousseau | LB | 26 | Miami |
| 56 | Javon Solomon | LB | 25 | Troy |
| 44 | Joe Andreessen | LB | 26 | Buffalo |
| 52 | Kaleb Elarms-Orr | LB | 23 | TCU |
| 8 | Terrel Bernard | LB | 27 | Baylor |
| 99 | TJ Parker | LB | 22 | Clemson |
| 22 | C.J. Gardner-Johnson | S | 28 | Florida |
| 24 | Cole Bishop | S | 23 | Utah |
| 3 | Damar Hamlin | S | 28 | Pittsburgh |
| 29 | Jalon Kilgore | S | 21 | South Carolina |
| 28 | Sam Franklin Jr. | S | 30 | Temple |
| 43 | Dorian Strong | CB | 24 | Virginia Tech |
| 37 | Jordan Hancock | CB | 23 | Ohio State |
| 92 | Zane Durant | DT | 22 | Penn State |
| 14 | Tyrell Shavers | WR | 27 | San Diego State |
| 63 | Austin Corbett | C | 30 | Nevada |
| 66 | Connor McGovern | C | 28 | Penn State |
| 53 | Lloyd Cushenberry III | C | 28 | LSU |
| 60 | Ar'maj Reed-Adams | G | 24 | Texas A&M |
| 64 | O'Cyrus Torrence | G | 26 | Florida |
| 70 | Alec Anderson | OT | 27 | UCLA |
| 73 | Dion Dawkins | OT | 32 | Temple |
| 74 | Jude Bowry | OT | 23 | Boston College |
| 79 | Spencer Brown | OT | 28 | Northern Iowa |
| 68 | Tylan Grable | OT | 27 | UCF |
| 17 | Josh Allen | QB | 30 | Wyoming |
| 11 | Kyle Allen | QB | 30 | Houston |
| 4 | James Cook III | RB | 27 | Georgia |
| 7 | Ray Davis | RB | 26 | Kentucky |
| 26 | Ty Johnson | RB | 29 | Maryland |
| 86 | Dalton Kincaid | TE | 27 | Utah |
| 88 | Dawson Knox | TE | 29 | Ole Miss |
| 85 | Jackson Hawes | TE | 25 | Georgia Tech |
| 83 | Keleki Latu | TE | 24 | Washington |
| 2 | DJ Moore | WR | 29 | Maryland |
| 19 | Greg Dortch | WR | 28 | Wake Forest |
| 5 | Joshua Palmer | WR | 27 | Tennessee |
| 0 | Keon Coleman | WR | 23 | Florida State |
| 10 | Khalil Shakir | WR | 26 | Boise State |
| 13 | Skyler Bell | WR | 24 | UConn |
| A.J. Woods | CB | 25 | Pittsburgh | |
| 30 | Anthony Kendall | CB | 26 | Baldwin Wallace |
| 93 | Austin Johnson | DT | 32 | Penn State |
| 72 | Phidarian Mathis | DT | 28 | Alabama |
| Brock Lampe | FB | 23 | Northern Illinois | |
| 49 | Keonta Jenkins | LB | 24 | Virginia Tech |
| 45 | Shaq Thompson | LB | 32 | Washington |
| 77 | Chase Lundt | OT | 26 | UConn |
| 67 | Travis Clayton | OT | 25 | -- |
| 6 | Shane Buechele | QB | 28 | SMU |
| 20 | Frank Gore Jr. | RB | 24 | Southern Miss |
| 25 | Geno Stone | S | 27 | Iowa |
| 84 | Ja'Mori Maclin | WR | 25 | Kentucky |
| 89 | Stephen Gosnell | WR | 24 | Virginia Tech |
| 81 | Trent Sherfield | WR | 30 | Vanderbilt |
| 69 | Reid Ferguson | LS | 32 | LSU |
| 39 | Tommy Doman Jr. | P | 24 | Florida |
| 16 | Tyler Bass | PK | 29 | Georgia Southern |
Tyrell ShaversPhysically unable to perform
Knee - ACL - Physically Unable to Perform. Expected Return - Week 8
Zane DurantInjured list
I.L. - Undisclosed
T.J. SandersQuestionable
Shoulder - Full Practice on Friday. Questionable for Week 6 at Las Vegas
Dee AlfordQuestionable
Ankle - Limited Practice on Friday. Questionable for Week 6 at Las Vegas
DJ MooreQuestionable
Shoulder - AC Joint - Limited Practice on Friday. Questionable for Week 6 at Las Vegas
Ed OliverQuestionable
Knee - Limited Practice on Friday. Questionable for Week 6 at Las Vegas
Josh PalmerQuestionable
Shoulder - Questionable for Week 6 at Las Vegas
Demetrius Flannigan-FowlesQuestionable
Undisclosed - Questionable for Week 5 at L.A. Rams
Dorian StrongNon-football injury
Neck - NFI-R for Week 6 at Las Vegas
Grant DuBoseQuestionable
Shoulder - Questionable for Week 5 at L.A. Rams
Jalen VirgilQuestionable
Undisclosed - Questionable for Week 5 at L.A. Rams
Jordan HancockInjured list
I.L. - Hamstring
Jordan PoyerQuestionable
Hamstring - Questionable for Week 5 at L.A. Rams
